
The following is the schedule for the conference, current as of 29 October. 2001. All activities will be held on the Caltech campus.
| Sunday, November 4, 2001 (Location: Beckman Institute) | |
Tutorials
(two parallel tracks, see Tutorials
page for detailed schedule):
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| Monday, November 5, 2001 (Location: Ramo Auditorium) | |
| 08:30 - 08:45 | Welcome
to the First Day of ICSB2001, the Second International Conference on Systems Biology |
| 08:45 - 09:00 | Opening Remarks: Hiroaki Kitano (The Systems Biology Institute) |
| 09:00 - 10:00 | Keynote Speech I: Alfred Gilman (UT Southwestern, AFCS) |
| 10:00 - 10:20 | Coffee/Tea Break |
| Session I: Modeling Signal Transduction | |
| 10:20 - 10:30 | Overview of Session: Melvin Simon (Caltech, Biology) |
| 10:30 - 11:05 | Uri
Alon (Weizmann Institute) Reverse-engineering the gene regulation network of E. coli |
| 11:05 - 11:40 | Dennis
Bray (Cambridge University) Modeling molecular events in a small volume of living cytoplasm |
| 11:40 - 12:15 | Peter
Devreotes (Johns Hopkins
University) Mechanisns of directional sensing in eucaryotic cells |
| 12:15 - 13:45 | Lunch |
| Session II: Software and Theory in Systems Biology | |
| 13:45 - 13:50 | Overview of Session: John Doyle (Caltech, EAS) |
| 13:50 - 14:25 | Joel
Stiles (Pittsburgh Supercomputing
Center) Monte Carlo simulation of realistic cellular microphysiology |
| 14:25 - 15:00 | Hiroaki
Kitano (The Systems
Biology Institute) SBW/SBML: a software platform and standard for systems biology |
| 15:00 - 15:35 | Shoshana
J. Wodak (Universite Libre
de Bruxelles) Representing and analyzing biological function with aMAZE, a database of molecular interactions and processes |
| 15:35 - 15:50 | Coffee/Tea Break |
| 15:50 - 16:25 | Jan-Hendrik
Hofmeyr (Stellenbosch University) Metabolic control analysis: a tool for understanding cellular behaviour, control and regulation |
| 16:25 - 17:00 | Michael
Savageau (University
of Michigan) Alternative designs for a genetic switch: analysis of switching times using the piecewise power-law representation within Biochemical Systems Theory |
| 17:00 - 19:30 | Poster Session I (Beckman Institute Courtyard) |
| 18:00 - 19:30 | Social Gathering (Beckman Institute Courtyard) |
| Tuesday, November 6, 2001 (Location: Ramo Auditorium) | |
| 08:45 - 09:00 | Welcome & Announcements for the Second Day |
| 09:00 - 10:00 | Keynote
Speech II: David
Botstein (Stanford
University) Extracting biological information from genome-wide gene expression studies |
| 10:00 - 10:20 | Coffee/Tea Break |
| Session III: Experimental Technologies for Systems Biology | |
| 10:20 - 10:30 | Overview of Session: Stephen R. Quake (Caltech, EAS) |
| 10:30 - 11:05 | Rudy
Aebersold (Institute
for Systems Biology) Quantitative proteome analysis: new technology and applications |
| 11:05 - 11:40 | David
Lockhart (Aventa Biosciences) Quantitative gene expression profiling in the brain |
| 11:40 - 12:15 | Tobias
Meyer (Stanford
University) Dynamic properties of cellular signaling networks |
| 12:15 - 13:50 | Lunch |
| Session IV: Modeling Cellular Physiology | |
| 13:50 - 14:00 | Overview of Session: Ray Deschaies (Caltech, Biology) |
| 14:00 - 14:35 |
John
Tyson (Virginia Tech) |
| 14:35 - 15:10 | Lucy
Shapiro (Stanford
University) A systems engineering approach to the bacterial cell cycle: defining the genetic circuitry |
| 15:10 - 15:30 | Coffee/Tea Break |
| 15:30 - 16:05 | Douglas
Lauffenburger (MIT) Receptor, ligand, and signaling pathway dynamics in the Epidermal Growth Factor system |
| 16:05 - 16:40 | Hans
Westerhoff (Vrije
University Amsterdam) Understanding what we already know about the living cell: cellular bioinformatics, computational biochemistry, and the Silicon Cell |
| 16:45 - 18:45 | Poster Session II (Beckman Institute Courtyard) |
| 19:00 - 22:00 | Banquet
(Athenaeum) Welcome & Introduction by Caltech President David Baltimore Dinner Speaker: Marvin Cassman (Director, National Institute of General Medical Sciences, National Institutes of Health) |
| Wednesday, November 7, 2001 | |
| 08:45 - 09:00 | Welcome & Announcements for the Final Day |
| 09:00 - 10:00 | Keynote
Speech III: Adam
Arkin (Lawrence Berkeley Laboratories) Network bioinformatics: from effect detection to comparative regulation |
| Session V: Genomics and Systems Biology | |
| 10:00 - 10:10 | Overview of Session: Barbara Wold (Caltech, Biology) |
| 10:10 - 10:45 | David
Eisenberg (UCLA) Protein interactions |
| 10:45 - 11:00 | Coffee/Tea Break |
| 11:00 - 11:35 | Eric
Davidson (Caltech,
Biology) Towards a DNA sequence-based cis-regulatory network model for a major developmental specification process in the sea urchin embryo |
| 11:35 - 12:10 | Andrew
Murray (Harvard University) Experimental evolution in yeast: a progress report |
| 12:10 - 12:45 | Leroy
Hood (Institute
for Systems Biology) Genomics, proteomics, and systems biology |
| 12:45 - 14:25 | Lunch |
| Session VI: Fresh Perspectives in Systems Biology | |
| 14:25 - 14:30 | Overview of Session: Eric Mjolsness (JPL) |
| 14:30 - 14:55 | Birgit
Schoeberl (MIT) A mathematical vision of TNF receptor interaction |
| 14:55 - 15:20 | Pablo
Iglesias (Johns Hopkins) Spatial sensing of chemotactic gradients: a reaction-diffusion model |
| 15:20 - 15:45 | Joerg
Stelling (Max Planck Institute
for Dynamics of Complex Technical Systems) Robustness vs. identifiability of regulatory modules? |
| 15:45 - 16:00 | Coffee/Tea Break |
| 16:00 - 16:25 | David
Wild (Keck Graduate Institute) Modeling biological responses using gene expression profiling and linear dynamical systems |
| 16:25 - 16:50 | Sarah
Teichmann (MRC Laboratory
of Molecular Biology) Comparison of the small molecule metabolic pathways in Escherichia coli and Saccharomyces cerevisiae: nonortho-logous displacements, gene fusions and protein interactions |
| 16:50 - 17:15 | Eric
Mjolsness (JPL) Developmental simulations with Cellerator |
| 17:15 - 17:30 | Closing
Remarks Hiroaki Kitano (The Systems Biology Institute) |